When is it not possible to apply Botox? - Botox®/Dysport® - Smoothing out the wrinkles - Forums & Discussion 

Contraindications to BOTOX® injections Contraindications include prior allergic reaction, injection into areas of infection or inflammation, pregnancy (category C - safety for use during pregnancy has not been established), or breastfeeding. Women who inadvertently were injected during pregnancy thus far have had uneventful deliveries, and to date no teratogenicity has been attributed to botulinum toxin. Nonetheless, it is a category C medication, and delay of injections is recommended until pregnancy is complete and breastfeeding has ended. Relative contraindications Treat patients with diseases of the neuromuscular junction (eg, myasthenia gravis) cautiously because underlying generalized weakness can be exacerbated, and local weakness at injection sites can occur more than otherwise expected. Some medications decrease neuromuscular transmission and generally should be avoided in patients treated with botulinum toxin. These include aminoglycosides, penicillamine, quinine, and calcium channel blockers.

You should not be treated if: - allergic to any of the ingredients in products containing botulinum toxin. - if you had an allergic reaction to any other botulinum toxin product - if you have a skin infection at the planned injection site - if you have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig's disease], myasthenia gravis or Lambert-Eaton syndrome). - allergies to any botulinum toxin product - had any side effect from any botulinum toxin product in the past ,a breathing problem, such as asthma or emphysema, swallowing problems - if you have bleeding problems - if you have plans to have surgery or had surgery on your face - if you have weakness of your forehead muscles, such as trouble raising your eyebrows drooping eyelids, any other change in the way your face normally looks - pregnant or plan to become pregnant, are breast-feeding or plan to breastfeed.

Contraindications include prior allergic reaction, injection into areas of infection or inflammation, pregnancy (category C - safety for use during pregnancy has not been established). Patients with neuro-muscular disease should be studied carefully before BTX application. Some medications decrease neuromuscular transmission and generally should be avoided in patients treated with botulinum toxin, such as aminoglycosides, penicillamine, quinine, and calcium channel blockers.

Pregnancy, myasthenia gravis, local skin infections, etc. Your physician will discuss that more detailed with you.

when there a history of drug sensitivity,or the general health of the patient is not good.